Transcriptional regulation of the ABCC6 gene and the background of impaired function of missense disease-causing mutations

The human ATP-binding cassette family C member 6 (ABCC6) gene encodes an ABC transporter protein expressed primarily in the liver and to a lesser extent in the kidneys and the intestines. We review here the mechanisms of this restricted tissue-specific expression and the role of hepatocyte nuclear f...

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Bibliographic Details
Main Authors: Arányi, Tamás, Bacquet, Caroline, de Boussac, Hugues, Ratajewski, Marcin, Pomozi, Viola, Fülöp, Krisztina, Brampton, Christopher N., Pulaski, Lukasz, Saux, Olivier Le, Váradi, András
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593682/
https://ncbi.nlm.nih.gov/pubmed/23483032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00027
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