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Transcriptional regulation of the ABCC6 gene and the background of impaired function of missense disease-causing mutations
The human ATP-binding cassette family C member 6 (ABCC6) gene encodes an ABC transporter protein expressed primarily in the liver and to a lesser extent in the kidneys and the intestines. We review here the mechanisms of this restricted tissue-specific expression and the role of hepatocyte nuclear f...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593682/ https://ncbi.nlm.nih.gov/pubmed/23483032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00027 |
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