The ERK1/2-Hepatocyte Nuclear Factor 4α Axis Regulates Human ABCC6 Gene Expression in Hepatocytes

ABCC6 mutations are responsible for the development of pseudoxanthoma elasticum, a rare recessive disease characterized by calcification of elastic fibers. Although ABCC6 is mainly expressed in the liver the disease has dermatologic, ocular, and cardiovascular symptoms. We investigated the transcrip...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: de Boussac, Hugues, Ratajewski, Marcin, Sachrajda, Iwona, Köblös, Gabriella, Tordai, Attila, Pulaski, Lukasz, Buday, László, Váradi, András, Arányi, Tamás
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Gene Regulation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906271/
https://ncbi.nlm.nih.gov/pubmed/20463007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105593
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk