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Multi-Site Prenylation of 4-Substituted Tryptophans by Dimethylallyltryptophan Synthase

The aromatic prenyltransferase dimethylallyltryptophan synthase in Claviceps purpurea catalyzes the normal prenylation of tryptophan at C4 of the indole nucleus in the first committed step of ergot alkaloid biosynthesis. 4-Methyltryptophan is a competitive inhibitor of the enzyme that has been used...

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Bibliografski detalji
Glavni autori: Rudolf, Jeffrey D., Wang, Hong, Poulter, C. Dale
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593668/
https://ncbi.nlm.nih.gov/pubmed/23301871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja310734n
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