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Multi-Site Prenylation of 4-Substituted Tryptophans by Dimethylallyltryptophan Synthase
The aromatic prenyltransferase dimethylallyltryptophan synthase in Claviceps purpurea catalyzes the normal prenylation of tryptophan at C4 of the indole nucleus in the first committed step of ergot alkaloid biosynthesis. 4-Methyltryptophan is a competitive inhibitor of the enzyme that has been used...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593668/ https://ncbi.nlm.nih.gov/pubmed/23301871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja310734n |
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