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The Escherichia coli Replisome is Inherently DNA Damage Tolerant

The Escherichia coli DNA replication machinery must frequently overcome template lesions under normal growth conditions. Yet, the outcome of a collision between the replisome and a leading-strand template lesion remains poorly understood. Here we demonstrate that a single, site-specific, cyclobutane...

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Bibliografiset tiedot
Päätekijät: Yeeles, Joseph T.P., Marians, Kenneth J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593629/
https://ncbi.nlm.nih.gov/pubmed/21998391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1209111
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