Inhibition of T Cell Protein Tyrosine Phosphatase Enhances Interleukin-18-Dependent Hematopoietic Stem Cell Expansion

The clinical application of hematopoietic progenitor cell-based therapies for the treatment of hematological diseases is hindered by current protocols, which are cumbersome and have limited efficacy to augment the progenitor cell pool. We report that inhibition of T-cell protein tyrosine phosphatase...

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Bibliographic Details
Main Authors: Bourdeau, Annie, Trop, Sébastien, Doody, Karen M, Dumont, Daniel J, Tremblayef, Michel L
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2013
Subjects:
Regenerative Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593175/
https://ncbi.nlm.nih.gov/pubmed/23135963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1276
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