NMR-based metabolomics of urine in a mouse model of Alzheimer’s disease: identification of oxidative stress biomarkers

Alzheimer’s disease (AD) is the most common cause of neurodegenerative dementia among elderly patients. A biomarker for the disease could make diagnosis easier and more accurate, and accelerate drug discovery. In this study, NMR-based metabolomics analysis in conjunction with multivariate statistics...

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Detalhes bibliográficos
Main Authors: Fukuhara, Kiyoshi, Ohno, Akiko, Ota, Yosuke, Senoo, Yuya, Maekawa, Keiko, Okuda, Haruhiro, Kurihara, Masaaki, Okuno, Alato, Niida, Shumpei, Saito, Yoshiro, Takikawa, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593130/
https://ncbi.nlm.nih.gov/pubmed/23526113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.12-118
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