Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD), the most common cause of dementia among neurodegenerative diseases, afflicts millions of elderly people worldwide. In addition to amyloid-beta (Aβ) peptide and phosphorylated tau, lipid dysregulation is suggested to participate in AD pathogenesis. However, alter...

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Autors principals: Tajima, Yoko, Ishikawa, Masaki, Maekawa, Keiko, Murayama, Mayumi, Senoo, Yuya, Nishimaki-Mogami, Tomoko, Nakanishi, Hiroki, Ikeda, Kazutaka, Arita, Makoto, Taguchi, Ryo, Okuno, Alato, Mikawa, Ryuta, Niida, Shumpei, Takikawa, Osamu, Saito, Yoshiro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668217/
https://ncbi.nlm.nih.gov/pubmed/23659495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-68
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