Glucosylceramide and Lysophosphatidylcholines as Potential Blood Biomarkers for Drug-Induced Hepatic Phospholipidosis

Drug-induced phospholipidosis is one of the major concerns in drug development and clinical treatment. The present study involved the use of a nontargeting lipidomic analysis with liquid chromatography-mass spectrometry to explore noninvasive blood biomarkers for hepatic phospholipidosis from rat pl...

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Udgivet i:Toxicol Sci
Main Authors: Saito, Kosuke, Maekawa, Keiko, Ishikawa, Masaki, Senoo, Yuya, Urata, Masayo, Murayama, Mayumi, Nakatsu, Noriyuki, Yamada, Hiroshi, Saito, Yoshiro
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
125
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271040/
https://ncbi.nlm.nih.gov/pubmed/24980264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu132
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