NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses

The interplay between innate and adaptive immunity is important in multiple sclerosis (MS). The inflammasome complex, which activates caspase-1 to process pro–IL-1β and pro–IL-18, is rapidly emerging as a pivotal regulator of innate immunity, with nucleotide-binding domain, leucine-rich repeat conta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gris, Denis, Ye, Zhengmao, Iocca, Heather A., Wen, Haitao, Craven, Robin R., Gris, Pavel, Huang, Max, Schneider, Monika, Miller, Stephen D., Ting, Jenny P.-Y.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593010/
https://ncbi.nlm.nih.gov/pubmed/20574004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904145
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