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Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

BACKGROUND: There is consensus that experimental autoimmune encephalomyelitis (EAE) can be mediated by myelin specific T cells of Th1 as well as of Th17 phenotype, but the contribution of either subset to the pathogenic process has remained controversial. In this report, we compare functional differ...

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Hauptverfasser: Domingues, Helena S., Mues, Marsilius, Lassmann, Hans, Wekerle, Hartmut, Krishnamoorthy, Gurumoorthy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000428/
https://ncbi.nlm.nih.gov/pubmed/21209700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015531
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