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Pool-hmm: a Python program for estimating the allele frequency spectrum and detecting selective sweeps from next generation sequencing of pooled samples

Due to its cost effectiveness, next generation sequencing of pools of individuals (Pool-Seq) is becoming a popular strategy for genome-wide estimation of allele frequencies in population samples. As the allele frequency spectrum provides information about past episodes of selection, Pool-seq is also...

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Bibliographic Details
Main Authors: Boitard, Simon, Kofler, Robert, Françoise, Pierre, Robelin, David, Schlötterer, Christian, Futschik, Andreas
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592992/
https://ncbi.nlm.nih.gov/pubmed/23311589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1755-0998.12063
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