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Detecting Selective Sweeps: A New Approach Based on Hidden Markov Models

Detecting and localizing selective sweeps on the basis of SNP data has recently received considerable attention. Here we introduce the use of hidden Markov models (HMMs) for the detection of selective sweeps in DNA sequences. Like previously published methods, our HMMs use the site frequency spectru...

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Bibliographic Details
Main Authors: Boitard, Simon, Schlötterer, Christian, Futschik, Andreas
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666521/
https://ncbi.nlm.nih.gov/pubmed/19204373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.100032
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