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Early Differentiated CD138(high)MHCII(+)IgG(+) Plasma Cells Express CXCR3 and Localize into Inflamed Kidneys of Lupus Mice

Humoral responses are central to the development of chronic autoimmune diseases such as systemic lupus erythematosus. Indeed, autoantibody deposition is responsible for tissue damage, the kidneys being one of the main target organs. As the source of pathogenic antibodies, plasma cells are therefore...

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Autors principals: Lacotte, Stéphanie, Decossas, Marion, Le Coz, Carole, Brun, Susana, Muller, Sylviane, Dumortier, Hélène
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592892/
https://ncbi.nlm.nih.gov/pubmed/23520491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058140
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