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Phospholipid Metabolites in Recurrent Glioblastoma: In Vivo Markers Detect Different Tumor Phenotypes before and under Antiangiogenic Therapy

PURPOSE: Metabolic changes upon antiangiogenic therapy of recurrent glioblastomas (rGBMs) may provide new biomarkers for treatment efficacy. Since in vitro models showed that phospholipid membrane metabolism provides specific information on tumor growth we employed in-vivo MR-spectroscopic imaging (...

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書誌詳細
主要な著者: Hattingen, Elke, Bähr, Oliver, Rieger, Johannes, Blasel, Stella, Steinbach, Joachim, Pilatus, Ulrich
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592858/
https://ncbi.nlm.nih.gov/pubmed/23520454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056439
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