Phospholipid Metabolites in Recurrent Glioblastoma: In Vivo Markers Detect Different Tumor Phenotypes before and under Antiangiogenic Therapy

PURPOSE: Metabolic changes upon antiangiogenic therapy of recurrent glioblastomas (rGBMs) may provide new biomarkers for treatment efficacy. Since in vitro models showed that phospholipid membrane metabolism provides specific information on tumor growth we employed in-vivo MR-spectroscopic imaging (...

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Bibliografiska uppgifter
Huvudupphovsmän: Hattingen, Elke, Bähr, Oliver, Rieger, Johannes, Blasel, Stella, Steinbach, Joachim, Pilatus, Ulrich
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592858/
https://ncbi.nlm.nih.gov/pubmed/23520454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056439
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