Phospholipid Metabolites in Recurrent Glioblastoma: In Vivo Markers Detect Different Tumor Phenotypes before and under Antiangiogenic Therapy

PURPOSE: Metabolic changes upon antiangiogenic therapy of recurrent glioblastomas (rGBMs) may provide new biomarkers for treatment efficacy. Since in vitro models showed that phospholipid membrane metabolism provides specific information on tumor growth we employed in-vivo MR-spectroscopic imaging (...

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Библиографические подробности
Главные авторы: Hattingen, Elke, Bähr, Oliver, Rieger, Johannes, Blasel, Stella, Steinbach, Joachim, Pilatus, Ulrich
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592858/
https://ncbi.nlm.nih.gov/pubmed/23520454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056439
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