Bevacizumab impairs oxidative energy metabolism and shows antitumoral effects in recurrent glioblastomas: a (31)P/(1)H MRSI and quantitative magnetic resonance imaging study

Bevacizumab shows unprecedented rates of response in recurrent glioblastomas (GBM), but the detailed mechanisms are still unclear. We employed in vivo magnetic resonance spectroscopic imaging (MRSI) and quantitative magnetic resonance imaging to investigate whether bevacizumab alters oxygen and ener...

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Detalhes bibliográficos
Main Authors: Hattingen, Elke, Jurcoane, Alina, Bähr, Oliver, Rieger, Johannes, Magerkurth, Jörg, Anti, Sandra, Steinbach, Joachim P., Pilatus, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223092/
https://ncbi.nlm.nih.gov/pubmed/21890539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor132
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