Bevacizumab impairs oxidative energy metabolism and shows antitumoral effects in recurrent glioblastomas: a (31)P/(1)H MRSI and quantitative magnetic resonance imaging study

Bevacizumab shows unprecedented rates of response in recurrent glioblastomas (GBM), but the detailed mechanisms are still unclear. We employed in vivo magnetic resonance spectroscopic imaging (MRSI) and quantitative magnetic resonance imaging to investigate whether bevacizumab alters oxygen and ener...

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Bibliografiske detaljer
Main Authors: Hattingen, Elke, Jurcoane, Alina, Bähr, Oliver, Rieger, Johannes, Magerkurth, Jörg, Anti, Sandra, Steinbach, Joachim P., Pilatus, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Clinical Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223092/
https://ncbi.nlm.nih.gov/pubmed/21890539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor132
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