Recombinant Vectors Based on Porcine Adeno-Associated Viral Serotypes Transduce the Murine and Pig Retina

Recombinant adeno-associated viral (AAV) vectors are known to safely and efficiently transduce the retina. Among the various AAV serotypes available, AAV2/5 and 2/8 are the most effective for gene transfer to photoreceptors (PR), which are the most relevant targets for gene therapy of inherited reti...

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Hauptverfasser: Puppo, Agostina, Bello, Alexander, Manfredi, Anna, Cesi, Giulia, Marrocco, Elena, Corte, Michele Della, Rossi, Settimio, Giunti, Massimo, Bacci, Maria Laura, Simonelli, Francesca, Surace, Enrico Maria, Kobinger, Gary P., Auricchio, Alberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592811/
https://ncbi.nlm.nih.gov/pubmed/23520549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059025
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