Combined Rod and Cone Transduction by Adeno-Associated Virus 2/8

Gene transfer to both cone and rod photoreceptors (PRs) is essential for gene therapy of inherited retinal degenerations that are caused by mutations in genes expressed in both PR types. Vectors based on the adeno-associated virus (AAV) efficiently transduce PRs of different species. However, these...

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Detalhes bibliográficos
Main Authors: Manfredi, Anna, Marrocco, Elena, Puppo, Agostina, Cesi, Giulia, Sommella, Andrea, Della Corte, Michele, Rossi, Settimio, Giunti, Massimo, Craft, Cheryl M., Bacci, Maria Laura, Simonelli, Francesca, Surace, Enrico M., Auricchio, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868409/
https://ncbi.nlm.nih.gov/pubmed/24067103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2013.154
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