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DNA expansions generated by human Polµ on iterative sequences

Polµ is the only DNA polymerase equipped with template-directed and terminal transferase activities. Polµ is also able to accept distortions in both primer and template strands, resulting in misinsertions and extension of realigned mismatched primer terminus. In this study, we propose a model for hu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aza, Ana, Martin, Maria Jose, Juarez, Raquel, Blanco, Luis, Terrados, Gloria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592450/
https://ncbi.nlm.nih.gov/pubmed/23143108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1054
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