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Individual N-Glycans Added at Intervals along the Stalk of the Nipah Virus G Protein Prevent Fusion but Do Not Block the Interaction with the Homologous F Protein

The promotion of membrane fusion by most paramyxoviruses requires an interaction between the viral attachment and fusion (F) proteins to enable receptor binding by the former to trigger the activation of the latter for fusion. Numerous studies demonstrate that the F-interactive sites on the Newcastl...

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Detalhes bibliográficos
Main Authors: Zhu, Qiyun, Biering, Scott B., Mirza, Anne M., Grasseschi, Brittany A., Mahon, Paul J., Lee, Benhur, Aguilar, Hector C., Iorio, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592174/
https://ncbi.nlm.nih.gov/pubmed/23283956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03084-12
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