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Cysteines in the Stalk of the Nipah Virus G Glycoprotein Are Located in a Distinct Subdomain Critical for Fusion Activation

Paramyxoviruses initiate entry through the concerted action of the tetrameric attachment glycoprotein (HN, H, or G) and the trimeric fusion glycoprotein (F). The ectodomains of HN/H/G contain a stalk region important for oligomeric stability and for the F triggering resulting in membrane fusion. Par...

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Detalhes bibliográficos
Main Authors: Maar, Dianna, Harmon, Brooke, Chu, David, Schulz, Belinda, Aguilar, Hector C., Lee, Benhur, Negrete, Oscar A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393546/
https://ncbi.nlm.nih.gov/pubmed/22496210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00076-12
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