Cysteines in the Stalk of the Nipah Virus G Glycoprotein Are Located in a Distinct Subdomain Critical for Fusion Activation

Paramyxoviruses initiate entry through the concerted action of the tetrameric attachment glycoprotein (HN, H, or G) and the trimeric fusion glycoprotein (F). The ectodomains of HN/H/G contain a stalk region important for oligomeric stability and for the F triggering resulting in membrane fusion. Par...

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Main Authors: Maar, Dianna, Harmon, Brooke, Chu, David, Schulz, Belinda, Aguilar, Hector C., Lee, Benhur, Negrete, Oscar A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393546/
https://ncbi.nlm.nih.gov/pubmed/22496210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00076-12
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