Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras.

Eitemau Tebyg

• Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation.
  gan: Khosravi-Far, R, et al.
  Cyhoeddwyd: (1996)
• Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation.
  gan: Khosravi-Far, R, et al.
  Cyhoeddwyd: (1995)
• The predicted DBL oncogene product defines a distinct class of transforming proteins.
  gan: Eva, A, et al.
  Cyhoeddwyd: (1988)
• Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.
  gan: Gulbins, E, et al.
  Cyhoeddwyd: (1994)
• MRL proteins cooperate with activated Ras in glia to drive distinct oncogenic outcomes
  gan: Taylor, E, et al.
  Cyhoeddwyd: (2017)