Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras.

Vav and Dbl are members of a novel class of oncogene proteins that share significant sequence identity in a approximately 250-amino-acid domain, designated the Dbl homology domain. Although Dbl functions as a guanine nucleotide exchange factor (GEF) and activator of Rho family proteins, recent evide...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Khosravi-Far, R, Chrzanowska-Wodnicka, M, Solski, P A, Eva, A, Burridge, K, Der, C J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7935402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.10.6848-6857.1994
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