Biophysical and Ultrastructural Characterization of Adeno-Associated Virus Capsid Uncoating and Genome Release

We describe biophysical and ultrastructural differences in genome release from adeno-associated virus (AAV) capsids packaging wild-type DNA, recombinant single-stranded DNA (ssDNA), or dimeric, self-complementary DNA (scDNA) genomes. Atomic force microscopy and electron microscopy (EM) revealed that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Horowitz, Eric D., Rahman, K. Shefaet, Bower, Brian D., Dismuke, David J., Falvo, Michael R., Griffith, Jack D., Harvey, Stephen C., Asokan, Aravind
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592113/
https://ncbi.nlm.nih.gov/pubmed/23269804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03017-12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados