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Tyrosine crosslinking reveals interfacial dynamics in adeno-associated viral capsids during infection

Viral capsid dynamics are often observed during infectious events such as cell surface attachment, entry and genome release. Structural analysis of adeno-associated virus (AAV), a helper-dependent parvovirus, revealed a cluster of surface-exposed tyrosine residues at the icosahedral two-fold symmetr...

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Bibliographic Details
Main Authors: Horowitz, Eric D., Finn, M.G., Asokan, Aravind
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376196/
https://ncbi.nlm.nih.gov/pubmed/22458529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb3000265
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