Tubulin Acetyltransferase αTAT1 Destabilizes Microtubules Independently of Its Acetylation Activity

Acetylation of α-tubulin at lysine 40 (K40) is a well-conserved posttranslational modification that marks long-lived microtubules but has poorly understood functional significance. Recently, αTAT1, a member of the Gcn5-related N-acetyltransferase superfamily, has been identified as an α-tubulin acet...

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Hlavní autoři: Kalebic, Nereo, Martinez, Concepcion, Perlas, Emerald, Hublitz, Philip, Bilbao-Cortes, Daniel, Fiedorczuk, Karol, Andolfo, Annapaola, Heppenstall, Paul A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592022/
https://ncbi.nlm.nih.gov/pubmed/23275437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01044-12
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