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Enzymatic and non-enzymatic activities of the tubulin acetyltransferase MEC-17 are required for microtubule organization and mechanosensation in C. elegans

BACKGROUND: Microtubules (MTs) are formed from the lateral association of 11–16 protofilament chains of tubulin dimers, with most cells containing 13-protofilament (13-p) MTs. How these different MTs are formed is unknown, although the number of protofilaments may depend on the nature of the α- and...

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Detalhes bibliográficos
Main Authors: Topalidou, Irini, Keller, Charles, Kalebic, Nereo, Nguyen, Ken C., Somhegyi, Hannah, Politi, Kristin A., Heppenstall, Paul, Hall, David H., Chalfie, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382010/
https://ncbi.nlm.nih.gov/pubmed/22658602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.03.066
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