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Pharmacokinetics of Intravenous Linezolid in Moderately to Morbidly Obese Adults

The pharmacokinetics of linezolid was assessed in 20 adult volunteers with body mass indices (BMI) of 30 to 54.9 kg/m(2) receiving 5 intravenous doses of 600 mg every 12 h. Pharmacokinetic analyses were conducted using compartmental and noncompartmental methods. The mean (±standard deviation) age, h...

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Detalhes bibliográficos
Main Authors: Bhalodi, Amira A., Papasavas, Pavlos K., Tishler, Darren S., Nicolau, David P., Kuti, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591894/
https://ncbi.nlm.nih.gov/pubmed/23254421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01453-12
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