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Influence of Morbid Obesity on the Single-Dose Pharmacokinetics of Daptomycin

The present study characterized the single-dose pharmacokinetics of daptomycin dosed as 4 mg/kg of total body weight (TBW) in seven morbidly obese and seven age-, sex-, race-, and serum creatinine-matched healthy subjects. The glomerular filtration rate (GFR) was measured for both groups following a...

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Detalhes bibliográficos
Main Authors: Pai, Manjunath P., Norenberg, Jeffrey P., Anderson, Tamara, Goade, Diane W., Rodvold, Keith A., Telepak, Robert A., Mercier, Renee-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932544/
https://ncbi.nlm.nih.gov/pubmed/17548489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00059-07
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