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Pharmacokinetics of Telavancin at Fixed Doses in Normal-Body-Weight and Obese (Classes I, II, and III) Adult Subjects

A recommended total-body-weight (TBW) dosing strategy for telavancin may not be optimal in obese patients. The primary objective of this study was to characterize and compare the pharmacokinetics (PK) of telavancin across four body size groups: normal to overweight and obese classes I, II, and III....

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Publicat a:Antimicrob Agents Chemother
Autors principals: Bunnell, Kristen L., Pai, Manjunath P., Sikka, Monica, Bleasdale, Susan C., Wenzler, Eric, Danziger, Larry H., Rodvold, Keith A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913990/
https://ncbi.nlm.nih.gov/pubmed/29311094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02475-17
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