Pharmacokinetics of Telavancin at Fixed Doses in Normal-Body-Weight and Obese (Classes I, II, and III) Adult Subjects

A recommended total-body-weight (TBW) dosing strategy for telavancin may not be optimal in obese patients. The primary objective of this study was to characterize and compare the pharmacokinetics (PK) of telavancin across four body size groups: normal to overweight and obese classes I, II, and III....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bunnell, Kristen L., Pai, Manjunath P., Sikka, Monica, Bleasdale, Susan C., Wenzler, Eric, Danziger, Larry H., Rodvold, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913990/
https://ncbi.nlm.nih.gov/pubmed/29311094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02475-17
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