Quantitative Contributions of Target Alteration and Decreased Drug Accumulation to Pseudomonas aeruginosa Fluoroquinolone Resistance

Quinolone antibiotics constitute a clinically successful and widely used class of broad-spectrum antibiotics; however, the emergence and spread of resistance increasingly limits the use of fluoroquinolones in the treatment and management of microbial disease. In this study, we evaluated the quantita...

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Bibliografiske detaljer
Main Authors: Bruchmann, Sebastian, Dötsch, Andreas, Nouri, Bianka, Chaberny, Iris F., Häussler, Susanne
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591863/
https://ncbi.nlm.nih.gov/pubmed/23274661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01581-12
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