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Presence of Suppressor HIV-Specific CD8(+) T Cells Is Associated with Increased PD-1 Expression on Effector CD8(+) T Cells

Mechanisms leading to the observed immune dysregulation in HIV-1 infection are not well understood. HIV-specific IL-10-positive CD8(+) T cells are increased in advanced HIV disease. We have previously reported that Gag-specific IL-10-positive CD8(+) T cells suppressed cytolysis. In this study we des...

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Detalhes bibliográficos
Main Authors: Elrefaei, Mohamed, Baker, Chris A. R., Jones, Norman G., Bangsberg, David R., Cao, Huyen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591725/
https://ncbi.nlm.nih.gov/pubmed/18490780
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