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Lymphocyte Activation Gene-3 Expression Defines a Discrete Subset of HIV-Specific CD8(+) T Cells That Is Associated with Lower Viral Load

Mechanisms leading to the observed immune dysregulation in chronic HIV infection are not well understood. The MHC-II class ligand, lymphocyte activation gene-3 (LAG-3, CD223), has been implicated in the complex regulation mechanism of immune functions. In this study, we describe a new population of...

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Библиографические подробности
Главные авторы: Peña, José, Jones, Norman G., Bousheri, Stephanie, Bangsberg, David R., Cao, Huyen
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046223/
https://ncbi.nlm.nih.gov/pubmed/24180338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0195
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