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Biochemical Analysis of Histone Deacetylase-independent Transcriptional Repression by MeCP2
MeCP2 is an abundant methyl-cytosine-guanine (CG)-binding protein and transcriptional repressor. We developed a biochemical system that exhibits CG methylation-specific transcriptional repression by purified human MeCP2. MeCP2 represses transcription by histone deacetylase (HDAC)-dependent and HDAC-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3591619/ https://ncbi.nlm.nih.gov/pubmed/23349465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.438697 |
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