Monitoring Therapy with MEK Inhibitor U0126 in a Novel Wilms Tumor Model in Wt1 Knockout Igf2 Transgenic Mice Using (18)F-FDG PET with Dual-Contrast Enhanced CT and MRI: Early Metabolic Response Without Inhibition of Tumor Growth

PURPOSE: The understanding of the role of genetic alterations in Wilms tumor development could be greatly advanced using a genetically engineered mouse models that can replicate the development and progression of this disease in human patients and can be monitored using non-invasive structural and m...

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Main Authors: Flores, Leo G., Yeh, Hsin-Hsien, Soghomonyan, Suren, Young, Daniel, Bankson, James, Hu, Qianghua, Alauddin, Mian, Huff, Vicki, Gelovani, Juri G.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591528/
https://ncbi.nlm.nih.gov/pubmed/22875335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-012-0588-5
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