Pyrimidine Biosynthesis Is Not an Essential Function for Trypanosoma brucei Bloodstream Forms

BACKGROUND: African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite. METHODOLOGY/PRINCIPAL FINDINGS: Pyrimidine requirements for growth were investigated using strictly...

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Detaylı Bibliyografya
Asıl Yazarlar: Ali, Juma A. M., Tagoe, Daniel N. A., Munday, Jane C., Donachie, Anne, Morrison, Liam J., de Koning, Harry P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591441/
https://ncbi.nlm.nih.gov/pubmed/23505454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058034
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