Characterization of Nasal Potential Difference in cftr Knockout and F508del-CFTR Mice

BACKGROUND: Treatments designed to correct cystic fibrosis transmembrane conductance regulator (CFTR) defects must first be evaluated in preclinical experiments in the mouse model of cystic fibrosis (CF). Mice nasal mucosa mimics the bioelectric defect seen in humans. The use of nasal potential diff...

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Detalhes bibliográficos
Main Authors: Saussereau, Emilie Lyne, Roussel, Delphine, Diallo, Siradiou, Debarbieux, Laurent, Edelman, Aleksander, Sermet-Gaudelus, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591431/
https://ncbi.nlm.nih.gov/pubmed/23505426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057317
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