Characterization of Nasal Potential Difference in cftr Knockout and F508del-CFTR Mice

BACKGROUND: Treatments designed to correct cystic fibrosis transmembrane conductance regulator (CFTR) defects must first be evaluated in preclinical experiments in the mouse model of cystic fibrosis (CF). Mice nasal mucosa mimics the bioelectric defect seen in humans. The use of nasal potential diff...

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Main Authors: Saussereau, Emilie Lyne, Roussel, Delphine, Diallo, Siradiou, Debarbieux, Laurent, Edelman, Aleksander, Sermet-Gaudelus, Isabelle
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591431/
https://ncbi.nlm.nih.gov/pubmed/23505426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057317
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