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Characterization of two rat models of cystic fibrosis—KO and F508del CFTR—Generated by Crispr‐Cas9
BACKGROUND: Genetically engineered animals are essential for gaining a proper understanding of the disease mechanisms of cystic fibrosis (CF). The rat is a relevant laboratory model for CF because of its zootechnical capacity, size, and airway characteristics, including the presence of submucosal gl...
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| Publicado no: | Animal Model Exp Med |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6930998/ https://ncbi.nlm.nih.gov/pubmed/31942562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ame2.12091 |
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