Progressive increases in the methylation status and heterochromatinization of the myoD CpG island during oncogenic transformation.

Alterations in DNA methylation patterns are one of the earliest and most common events in tumorigenesis. Overall levels of genomic methylation often decrease during transformation, but localized regions of increased methylation have been observed in the same tumors. We have examined changes in the m...

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הוצא לאור ב:	Mol Cell Biol
Principais autores:	Rideout, W M, Eversole-Cire, P, Spruck, C H, Hustad, C M, Coetzee, G A, Gonzales, F A, Jones, P A
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis 1994
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359141/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065347/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.6143-6152.1994
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