Progressive increases in the methylation status and heterochromatinization of the myoD CpG island during oncogenic transformation.

Alterations in DNA methylation patterns are one of the earliest and most common events in tumorigenesis. Overall levels of genomic methylation often decrease during transformation, but localized regions of increased methylation have been observed in the same tumors. We have examined changes in the m...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Rideout, W M, Eversole-Cire, P, Spruck, C H, Hustad, C M, Coetzee, G A, Gonzales, F A, Jones, P A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359141/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065347/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.6143-6152.1994
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