Genetic analysis of a phosphatidylinositol 3-kinase SH2 domain reveals determinants of specificity.

Phosphatidylinositol 3-kinase is an important element in both normal and oncogenic signal transduction. Polyomavirus middle T antigen transforms cells in a manner depending on association of its tyrosine 315 phosphorylation site with Src homology 2 (SH2) domains on the p85 subunit of the phosphatidy...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Yoakim, M, Hou, W, Songyang, Z, Liu, Y, Cantley, L, Schaffhausen, B
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359119/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065326/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.5929-5938.1994
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