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Genetic analysis of a phosphatidylinositol 3-kinase SH2 domain reveals determinants of specificity.

Phosphatidylinositol 3-kinase is an important element in both normal and oncogenic signal transduction. Polyomavirus middle T antigen transforms cells in a manner depending on association of its tyrosine 315 phosphorylation site with Src homology 2 (SH2) domains on the p85 subunit of the phosphatidy...

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Bibliografiske detaljer
Main Authors: Yoakim, M, Hou, W, Songyang, Z, Liu, Y, Cantley, L, Schaffhausen, B
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC359119/
https://ncbi.nlm.nih.gov/pubmed/8065326
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