In vivo inhibition of trypanosome mitochondrial topoisomerase II: effects on kinetoplast DNA maxicircles.

Kinetoplast DNA, the mitochondrial DNA of trypanosomes, is a topologically complex structure composed of interlocked minicircles and maxicircles. We previously reported that etoposide, a potent inhibitor of topoisomerase II, promotes the cleavage of about 20% of network minicircle DNA (T. A. Shapiro...

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書目詳細資料

發表在:	Mol Cell Biol
Principais autores:	Shapiro, T A, Showalter, A F
格式:	Artigo
語言:	Inglês
出版:	Taylor & Francis 1994
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359115/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.5891-5897.1994
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