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Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis.

The N-terminal domain of the c-Myc protein has been reported to be critical for both the transactivation and biological functions of the c-Myc proteins. Through detailed phosphopeptide mapping analyses, we demonstrate that there is a cluster of four regulated and complex phosphorylation events on th...

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Библиографические подробности
Опубликовано в: :Mol Cell Biol
Главные авторы: Lutterbach, B, Hann, S R
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 1994
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359071/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035827/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.8.5510
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