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Resveratrol Potentiates Effect of Simvastatin on Inhibition of Mevalonate Pathway in Human Endometrial Stromal Cells

CONTEXT: Growth of endometriotic lesions in rodent model of endometriosis is inhibited by resveratrol, a natural polyphenol with antiproliferative and antiinflammatory properties, and simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) activity. OBJECTIVE: The object...

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Autori principali: Villanueva, Jesus A., Sokalska, Anna, Cress, Amanda B., Ortega, Israel, Bruner-Tran, Kaylon L., Osteen, Kevin G., Duleba, Antoni J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590465/
https://ncbi.nlm.nih.gov/pubmed/23386644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-3387
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