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Simvastatin Decreases Invasiveness of Human Endometrial Stromal Cells

Recently we reported that statins, the competitive inhibitors of the key enzyme regulating the mevalonate pathway, 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), decrease proliferation of human endometrial stromal (HES) cells. Furthermore, we found that simvastatin treatment reduces the nu...

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Bibliografske podrobnosti
Main Authors: Sokalska, Anna, Cress, Amanda, Bruner-Tran, Kaylon L., Osteen, Kevin G., Taylor, Hugh S., Ortega, Israel, Duleba, Antoni J.
Format: Artigo
Jezik:Inglês
Izdano: Society for the Study of Reproduction, Inc. 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406552/
https://ncbi.nlm.nih.gov/pubmed/22492974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.098806
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